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atcc 6303 fitness  (ATCC)


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    ATCC atcc 6303 fitness
    a , Schematic of the mouse infection model. Mice were intranasally (i.n.) primed with PBS or influenza A virus (IAV; 10 PFU) and one week later infected with S. pneumoniae <t>ATCC-6303.</t> Bacterial inocula were ∼1 × 10⁸ CFU (D39L) or ∼1 × 10⁶ CFU (ATCC-6303) for pneumococcal infection alone (Spn) and ∼1 × 10⁴ CFU (D39L) or ∼1 × 10³ CFU (ATCC-6303) for superinfected (SI) mice. Fomepizole (10 mg kg⁻¹ in 200 ul of PBS) or PBS were administered intraperitoneally at the time of bacterial infection and again 12 h post infection. Mice were euthanized 24 h after bacterial challenge. b,c , Lung (b) and spleen (c) bacterial burdens in mice infected with S. pneumoniae D39L. d,e , Lung (d) and spleen (e) bacterial burdens in mice infected with S. pneumoniae ATCC-6303. Data are pooled from at least two independent experiments. Dots indicate individual mice (lungs n = 12-26, spleens n = 6-12), bars represent geometric means with geometric s.d. (b-e) . Statistical significance was determined by two-tailed unpaired t -tests (b-e) .
    Atcc 6303 Fitness, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 580 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/atcc 6303 fitness/product/ATCC
    Average 96 stars, based on 580 article reviews
    atcc 6303 fitness - by Bioz Stars, 2026-06
    96/100 stars

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    1) Product Images from "Early metabolic reprogramming licenses Streptococcus pneumoniae for Influenza-driven superinfection"

    Article Title: Early metabolic reprogramming licenses Streptococcus pneumoniae for Influenza-driven superinfection

    Journal: bioRxiv

    doi: 10.64898/2026.01.10.698720

    a , Schematic of the mouse infection model. Mice were intranasally (i.n.) primed with PBS or influenza A virus (IAV; 10 PFU) and one week later infected with S. pneumoniae ATCC-6303. Bacterial inocula were ∼1 × 10⁸ CFU (D39L) or ∼1 × 10⁶ CFU (ATCC-6303) for pneumococcal infection alone (Spn) and ∼1 × 10⁴ CFU (D39L) or ∼1 × 10³ CFU (ATCC-6303) for superinfected (SI) mice. Fomepizole (10 mg kg⁻¹ in 200 ul of PBS) or PBS were administered intraperitoneally at the time of bacterial infection and again 12 h post infection. Mice were euthanized 24 h after bacterial challenge. b,c , Lung (b) and spleen (c) bacterial burdens in mice infected with S. pneumoniae D39L. d,e , Lung (d) and spleen (e) bacterial burdens in mice infected with S. pneumoniae ATCC-6303. Data are pooled from at least two independent experiments. Dots indicate individual mice (lungs n = 12-26, spleens n = 6-12), bars represent geometric means with geometric s.d. (b-e) . Statistical significance was determined by two-tailed unpaired t -tests (b-e) .
    Figure Legend Snippet: a , Schematic of the mouse infection model. Mice were intranasally (i.n.) primed with PBS or influenza A virus (IAV; 10 PFU) and one week later infected with S. pneumoniae ATCC-6303. Bacterial inocula were ∼1 × 10⁸ CFU (D39L) or ∼1 × 10⁶ CFU (ATCC-6303) for pneumococcal infection alone (Spn) and ∼1 × 10⁴ CFU (D39L) or ∼1 × 10³ CFU (ATCC-6303) for superinfected (SI) mice. Fomepizole (10 mg kg⁻¹ in 200 ul of PBS) or PBS were administered intraperitoneally at the time of bacterial infection and again 12 h post infection. Mice were euthanized 24 h after bacterial challenge. b,c , Lung (b) and spleen (c) bacterial burdens in mice infected with S. pneumoniae D39L. d,e , Lung (d) and spleen (e) bacterial burdens in mice infected with S. pneumoniae ATCC-6303. Data are pooled from at least two independent experiments. Dots indicate individual mice (lungs n = 12-26, spleens n = 6-12), bars represent geometric means with geometric s.d. (b-e) . Statistical significance was determined by two-tailed unpaired t -tests (b-e) .

    Techniques Used: Infection, Virus, Two Tailed Test



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    atcc 6303 fitness  (ATCC)
    96
    ATCC atcc 6303 fitness
    a , Schematic of the mouse infection model. Mice were intranasally (i.n.) primed with PBS or influenza A virus (IAV; 10 PFU) and one week later infected with S. pneumoniae <t>ATCC-6303.</t> Bacterial inocula were ∼1 × 10⁸ CFU (D39L) or ∼1 × 10⁶ CFU (ATCC-6303) for pneumococcal infection alone (Spn) and ∼1 × 10⁴ CFU (D39L) or ∼1 × 10³ CFU (ATCC-6303) for superinfected (SI) mice. Fomepizole (10 mg kg⁻¹ in 200 ul of PBS) or PBS were administered intraperitoneally at the time of bacterial infection and again 12 h post infection. Mice were euthanized 24 h after bacterial challenge. b,c , Lung (b) and spleen (c) bacterial burdens in mice infected with S. pneumoniae D39L. d,e , Lung (d) and spleen (e) bacterial burdens in mice infected with S. pneumoniae ATCC-6303. Data are pooled from at least two independent experiments. Dots indicate individual mice (lungs n = 12-26, spleens n = 6-12), bars represent geometric means with geometric s.d. (b-e) . Statistical significance was determined by two-tailed unpaired t -tests (b-e) .
    Atcc 6303 Fitness, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/atcc 6303 fitness/product/ATCC
    Average 96 stars, based on 1 article reviews
    atcc 6303 fitness - by Bioz Stars, 2026-06
    96/100 stars
    		  Buy from Supplier

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    a , Schematic of the mouse infection model. Mice were intranasally (i.n.) primed with PBS or influenza A virus (IAV; 10 PFU) and one week later infected with S. pneumoniae ATCC-6303. Bacterial inocula were ∼1 × 10⁸ CFU (D39L) or ∼1 × 10⁶ CFU (ATCC-6303) for pneumococcal infection alone (Spn) and ∼1 × 10⁴ CFU (D39L) or ∼1 × 10³ CFU (ATCC-6303) for superinfected (SI) mice. Fomepizole (10 mg kg⁻¹ in 200 ul of PBS) or PBS were administered intraperitoneally at the time of bacterial infection and again 12 h post infection. Mice were euthanized 24 h after bacterial challenge. b,c , Lung (b) and spleen (c) bacterial burdens in mice infected with S. pneumoniae D39L. d,e , Lung (d) and spleen (e) bacterial burdens in mice infected with S. pneumoniae ATCC-6303. Data are pooled from at least two independent experiments. Dots indicate individual mice (lungs n = 12-26, spleens n = 6-12), bars represent geometric means with geometric s.d. (b-e) . Statistical significance was determined by two-tailed unpaired t -tests (b-e) .

    Journal: bioRxiv

    Article Title: Early metabolic reprogramming licenses Streptococcus pneumoniae for Influenza-driven superinfection

    doi: 10.64898/2026.01.10.698720

    Figure Lengend Snippet: a , Schematic of the mouse infection model. Mice were intranasally (i.n.) primed with PBS or influenza A virus (IAV; 10 PFU) and one week later infected with S. pneumoniae ATCC-6303. Bacterial inocula were ∼1 × 10⁸ CFU (D39L) or ∼1 × 10⁶ CFU (ATCC-6303) for pneumococcal infection alone (Spn) and ∼1 × 10⁴ CFU (D39L) or ∼1 × 10³ CFU (ATCC-6303) for superinfected (SI) mice. Fomepizole (10 mg kg⁻¹ in 200 ul of PBS) or PBS were administered intraperitoneally at the time of bacterial infection and again 12 h post infection. Mice were euthanized 24 h after bacterial challenge. b,c , Lung (b) and spleen (c) bacterial burdens in mice infected with S. pneumoniae D39L. d,e , Lung (d) and spleen (e) bacterial burdens in mice infected with S. pneumoniae ATCC-6303. Data are pooled from at least two independent experiments. Dots indicate individual mice (lungs n = 12-26, spleens n = 6-12), bars represent geometric means with geometric s.d. (b-e) . Statistical significance was determined by two-tailed unpaired t -tests (b-e) .

    Article Snippet: These findings indicate that alcohol dehydrogenase activity contributes to ATCC-6303 fitness during superinfection, albeit to a lesser extent than in the D39 background.

    Techniques: Infection, Virus, Two Tailed Test